grindstone chemistry one pot synthesis of spiro

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Grindstone chemistry: one-pot synthesis of …

Grindstone chemistry: one-pot synthesis of spiro[diindenopyridine-indoline]triones and spiro[acenaphthylene-diindenopyridine]triones Author links open overlay panel Ramin Ghahremanzadeh Somayeh Ahadi Ghazaleh Imani Shakibaei Ayoob Bazgir Show more ...

Grindstone chemistry: one-pot synthesis of …

Grindstone chemistry: one-pot synthesis of spiro[diindenopyridine-indoline]triones and spiro[acenaphthylene-diindenopyridine]triones January 2010 Tetrahedron Letters 51(3):499-502

One‐pot and three‐component synthesis of …

Abstract A novel, clean, one‐pot and three‐component synthesis of new spiro[chromeno[2,3‐d]pyrimidine‐5,3′‐indoline]‐2′,6(7H)‐diones and spiro[chromeno[2,3‐c]pyrazole‐4,3

One‐pot synthesis of spiro‐acridine/indoline and indoline …

One‐pot synthesis of spiro‐acridine/indoline and indoline derivatives using (MWCNTs)‐COOH/La 2 O 3 hybrid as an effective catalyst Mahshid Abdoli Department of Chemistry, Qaemshahr Branch, Islamic Azad University, Qaemshahr, Iran

ACS Publications: Chemistry journals, books, and …

A highly efficient regio- and stereoselective spiroaziridine ring opening with 2-bromophenols and a subsequent tandem cyclization reaction was developed for the one-pot synthesis of enantiopure 3,4-dihydrospiro[benzo[b][1,4]oxazine-2,3′-oxindole] with excellent enantiopurity (ee up to >99%). It is further extended to asymmetric synthesis of NH-free 3,4-dihydrospiro[benzo[b][1,4]oxazine-2,3 ...

Stereoselective Synthesis of Spiro‐Azacycles Through …

A metal‐free one‐pot approach towards a highly stereoselective synthesis of N‐substituted spiro‐azacyclodienones, dihydro spiro‐azacyclodienones and spiro‐lactams have been reported in this present work.Phenyl tri‐methyl ammonium tri‐bromide (PTAB) as an ...

Grindstone Chemistry: Design, One-Pot Synthesis, and Promising …

One-pot synthesis of spiro[acridine-9,20-indoline]-1,3,8-trione derivatives. Anticancer Activity The compounds (1a–1j) were evaluated for anticancer activity. The MCF-7 cancer cell line was used to test all compounds at a cytotoxic assay dose of 100 M at 48 h

(PDF) Review of Synthesis of Spiro Heterocyclic …

A green, simple, efficient, one-pot, three-component method for the diversity-oriented synthesis of spiro[indoline-3,4 0 -thiopyrano [2,3-b]indole] derivatives 124 has been developed by the domino reaction of indoline-2-thione 123, isatin 1, and ethyl cyanoacetate or

Correction: Gobinath, P., et al. Grindstone Chemistry: …

Correction: Gobinath, P., et al. Grindstone Chemistry: Design, One-Pot Synthesis, and Promising Anticancer Activity of Spiro[acridine-9,2′-indoline]-1,3,8-trione Derivatives against the MCF-7 Cancer Cell Line. Molecules 2020, 25, 5862

Royal Society of Chemistry

Visible-light promoted one-pot synthesis of sulfonated spiro[4,5]trienones from propiolamides, anilines and sulfur dioxide under transition metal-free conditions† Yu Liu, * a Qiao-Lin Wang, a Zan Chen, a Quan Zhou,* a Bi-Quan Xiong, a Pan-Liang Zhang a and Ke-Wen Tang * a

One-pot synthesis of spiro(indoline-3,4''-pyrazolo[3,4 …

Aim: Inhibition of P53-mdm2 interaction will lead to cancer cell apoptosis. This strategy was achieved by reported spiro-oxindole derivatives. Materials & methods: Spiro(indoline-3,4''-pyrazolo[3,4-b]pyridine)-5''-carbonitrile derivatives (4a-i and 9a, b) were synthesized and screened for their in vitro anticancer activity.

Highly diastereoselective one-pot synthesis of …

 · Highly diastereoselective one-pot synthesis of spiro[cyclopenta[a]indene-2,2''-indene]diones from 1-indanones and aromatic aldehydes. Camps P(1), Domingo LR, Formosa X, Galdeano C, Gonzalez D, Muñoz-Torrero D, Segalés S, Font-Bardia M, Solans X.

ZnS Nanoparticles: An Efficient Catalyst for the One-Pot …

Title:ZnS Nanoparticles: An Efficient Catalyst for the One-Pot Synthesis of Spiro [Pyrrolidine-2, 3''-Oxindole] Derivatives from Phenothiazinyl Chalcones VOLUME: 10 ISSUE: 4 Author(s):K. L. Ameta, Biresh Kumar and Nitu S. Rathore Affiliation:Department of Chemistry, Faculty of Arts, Science and Commerce, Mody Institute of Technology & Science, Lakshmangarh - 332311, Rajasthan, India.

One‐pot synthesis of spiro‐acridine/indoline and indoline …

One‐pot synthesis of spiro‐acridine/indoline and indoline derivatives using (MWCNTs)‐COOH/La2O3 hybrid as an effective catalyst November 2020 Journal of Heterocyclic Chemistry 58(2)

Highly Diastereoselective One-Pot Synthesis of …

Highly Diastereoselective One-Pot Synthesis of Spiro{cyclopenta[a]indene-2,2''-indene}diones from 1-Indanones and Aromatic Aldehydes Pelayo Camps Luis R. Domingo Xavier Formosa Carles Galdeano Diana González Diego Muñoz-Torrero Sílvia Segalés

MOJ Bioorganic & Organic Chemistry

Synthesis of spiro indol derivatives In this study, we report the development of a solvent-free mechanochemical 31,32 approach for the multicomponent 33,34 synthesis of a series of Spiro indole derivatives in one step by the reaction of isatin, malononitrile and rhodanine using grindstone chemistry technique as shown in Scheme I..

Grindstone Chemistry: Design, One-Pot Synthesis, and …

View This Abstract Online Grindstone Chemistry: Design, One-Pot Synthesis, and Promising Anticancer Activity of Spiro[acridine-9,2''-indoline]-1,3,8-trione Derivatives against the MCF-7 Cancer Cell Line. Molecules. 2020; 25(24) (ISSN: 1420-3049) Gobinath P

Microwave‐assisted One‐pot, Three‐component …

The synthesis of a new series of spirocyclic molecules has been expediently accomplished via a one‐pot, three component 1,3‐dipolar cycloaddition reaction. 2‐Phenyl‐nitrochromene dipolarophiles were reacted with azomethine ylides, generated in situ by the

Molecules | Free Full-Text | Grindstone Chemistry: Design, …

Grindstone Chemistry: Design, One-Pot Synthesis, and Promising Anticancer Activity of Spiro[acridine-9,2′-indoline]-1,3,8-trione Derivatives Against the MCF-7 Cancer Cell Line

Correction: Gobinath, P., et al. Grindstone Chemistry: Design, One …

Grindstone Chemistry: Design, One-Pot Synthesis, and Promising Anticancer Activity of Spiro[acridine-9,20-indoline]-1,3,8-trione Derivatives against the MCF-7 Cancer Cell Line. Molecules 2020, 25, 5862. Molecules 2021, 26, 1131.https://doi / 10.3390

[PDF] Green preparation and structure elucidation of spiro …

One of the most important goals of green chemistry is to redesign environmentally benign synthetic methods which produce less chemical waste. For several years, synthetic chemists have been familiar with the concept of step economy which is the drive to increase the brevity and efficiency of a synthesis by a reduction in the number of synthetic steps. A step economic synthesis has the ...

One-Pot, Pseudo Four-Component Synthesis of a …

A one-pot, pseudo four-component method for the efficient and simple synthesis of spiro[diindeno[1,2-b:2′,1′-e]pyridine-11,3′-indoline]-2′,10,12-trione derivatives in refluxing acetonitrile is reported. The features of this procedure are mild reaction conditions, high yields of products, and operational simplicity.

(PDF) Grindstone Chemistry: Design, One-Pot Synthesis, …

PDF | In this study, the synthesis of one-pot 10-phenyl-3,4,6,7-tetrahydro-1H-spiro [acridine-9,2′-indoline]-1,3,8-trione derivatives was achieved via a... | Find, read and cite all the research ...

One‐pot synthesis of …

A one‐pot and pseudo four‐component synthesis of spiro[diindeno[1,2‐b :2′,1′‐e ]pyridine‐11,3′‐indoline]‐trione derivatives by cyclo‐condensation reaction of isatins, 1,3‐indandione, and ammonium acetate in refluxing acetic acid is reported. Please check your email for ...

One‐Pot Synthesis of Spiro[fluorine‐9,9''‐xanthene] …

This review summarizes a variety of economic and environmentally friendly one‐pot process to synthesize spiro[fluorine‐9,9''‐xanthene] derivatives (SFXs).

Grindstone chemistry: one-pot synthesis of …

Article "Grindstone chemistry: one-pot synthesis of spiro[diindenopyridine-indoline]triones and spiro[acenaphthylene-diindenopyridine]triones" Detailed information of the J-GLOBAL is a service based on the concept of Linking, Expanding, and Sparking, linking ...

Grindstone chemistry: one-pot synthesis of …

 · A one-pot, pseudo four-component, and simple synthesis of spiro [diindenopyridine-indoline]triones and spiro [acenaphthylene-diindenopyridine]triones via the reaction of 1,3-indandione, aromatic amines and isatins or acenaphthylene-1,2-dione using a ''Grindstone Chemistry'' method is reported.

Efficient Synthesis of Spiro[chromeno[2,3-d]pyrimidine …

Grindstone chemistry: one-pot synthesis of spiro[diindenopyridine-indoline]triones and spiro[acenaphthylene-diindenopyridine]triones. Tetrahedron Letters 2010, 51 (3), 499-502. DOI: 10.1016/j.tetlet.2009.11.041.